5-MeO-DMT is one of the most powerful psychedelic tryptamines in the world. The compound is found in several varieties of plants, but is most famously extracted from the venom of the Sonoran Desert Toad (Bufo alvarius.) For environmental reasons, our products are synthetic and are safely produced in a lab setting.
The difference between 5-MeO-DMT and N, N-DMT
5-MeO-DMT is often confused with the more widely known N, N-DMT and although they share commonalities in name and molecular structure, the experiences associated with the drugs are very different. While N, N-DMT is famous for its intense visions and sense of total disconnect from one’s body, the lesser known 5-MeO-DMT is known for producing strong tactile awareness, intense emotions, profound transpersonal/mystical experiences and ego death at breakthrough doses.
5-MeO-DMT is four to six times more powerful than N, N-DMT and produces a profoundly mystical experience at breakthrough doses. 5-MeO is not known for producing the type of visionary experiences and strong visual hallucinations associated with N, N-DMT, but it is possible to see complex geometric patterns and object distortion as is typical with use of psilocybin or LSD. Rarely, a phenomenon known as a white-out: a blinding white light in the place of typical psychedelic visuals can occur.
Dose Guideline for 5-Meo-DMT
Our 5-MeO DMT 300 mg cartridge will deliver approximately 2.5mg per 5 second inhalation or 0.5mg per second of inhalation time.
Dosing strategy for our 5-MeO-DMT vape cartridge:
- For a microdose, take one two-second inhalation.
- For a light dose, one five-second inhalation.
- For a medium dose, two five-second inhalations.
- For a breakthrough dose, three to four five-second inhalations.
What to expect on a 5-MeO-DMT Trip
5-MeO-DMT is intense and fast acting with onset of effects setting in within 15-30 seconds of inhalation. The peak of the experience typically occurs within one minute of dosing and can last up to 15 minutes. The effects tend to taper off after thirty minutes, and afterglow effects can be felt up to an hour. Most users will return to baseline around the hour mark.
It is very common to experience nausea at the onset of the experience, but this tends to taper off quickly. It is also likely you will temporarily experience spatial disorientation and a possible loss of motor function during the peak of the trip.
The experience produces strong, often overwhelming tactile awareness and sensitivity along with intense emotions. Ego dissolution (essentially, the ability to transcend our usual state of self-referential perception) and transpersonal or mystical experiences where the sense of self extends beyond the individual and encompasses all humankind, nature and the universe are commonly reported at breakthrough doses.
Benefits & Risks of using 5-MeO-DMT
As with the consumption of any psychedelic, there are inherent psychological and physiological risks involved with taking 5-MeO-DMT. Those who are prescribed and are actively taking MAOIs (monoamine oxidase inhibitors) or certain anti-depressants should not consume 5-MeO-DMT due to the possible, albeit rare risk of Serotonin Syndrome which can be fatal.
Due to the possibility of fluctuations in heart rate, the use of 5-MeO-DMT by those with heart conditions could prove dangerous and is discouraged.The breakthrough experience with the drug is extraordinarily powerful and as with other psychedelics at high doses, there is a possibility for emotional or psychological distress during or after a trip. Nausea is also a common side effect during the onset of the experience but tends to subside quickly and there is a possibility users may dissociate or interact inappropriately with their environments.
While there is limited research into the therapeutic use of 5-MeO-DMT, most people report profound, often life changing mystical experiences and a sense of oneness with the universe. When integrated properly, these types of experiences are often associated with a greater sense of empathy, a deeper connection with our communities and a heightened sense of satisfaction and overall wellbeing in day-to-day life.
In the early studies that have been conducted, study participants who reported being diagnosed with psychiatric disorders including post-traumatic stress disorder, depression, anxiety and substance abuse disorders claimed improvements to their symptoms following their 5-MeO-DMT sessions. A 2018 study from Brazil demonstrated a single 5-MeO-DMT dose stimulated the proliferation of nerve cells in the hippocampus of mice. This type of neurogenic and neuroplasticity promoting effect is thought to contribute to the antidepressant properties of serotonergic psychedelics similar to 5-MeO-DMT.
