5-MeO-DMT Vape Pen

5-MeO-DMT is a psychedelic tryptamine alkaloid — a methoxylated cousin of N,N-DMT that runs four to six times more powerful. It's best known from the secretions of the Sonoran Desert toad (Bufo alvarius), but it also occurs in dozens of plants, notably Anadenanthera, Phalaris, and Virola species, and at least one Amanita mushroom. It carries a long history of ceremonial use among indigenous Amazonians.

Venom harvesting has put real pressure on the Sonoran Desert toad, which is now listed as imperiled or locally extinct in several states. 5-MeO-DMT can be produced synthetically with no animal involved, so out of respect for this ecologically sensitive species, everything we offer is lab-synthesized.

Vaporized 5-MeO-DMT comes on within about 30 seconds, peaks between 1 and 15 minutes, and lasts up to half an hour. Unlike N,N-DMT it isn't known for visionary visuals — people describe a total perspective shift instead: an overwhelming sense of oneness with the universe, being outside time and space, ego dissolution, and at higher doses, out-of-body experience. Taken orally it does nothing; vaporizing is the route.

** Make sure when using the vape that all intake holes are completely saturated in the vape juice. This sometimes doesn't happen if you're laying down.** Charge your battery, press the power button five times to turn it on, and thread the cartridge on (or attach it via the magnetic 510 adapter on the premium battery). On the regular battery, press three times to cycle the voltage until the light blinks red — the highest setting. Press and hold the button while inhaling slowly but deeply, then hold the vapor in for 5–15 seconds — the longer you hold it, the more you absorb — and close your eyes as you exhale. Before you start: never attempt a breakthrough alone — have a sober trip-sitter present — and lie down somewhere comfortable first, because loss of coordination and spatial disorientation are normal at higher doses. Do not use 5-MeO-DMT with SSRIs, SNRIs, MAOIs, stimulants or alcohol, or if you or your family have a history of psychosis or a heart condition.

It's four to six times more powerful, and the character of the trip is distinct. Where N,N-DMT is famously visionary, 5-MeO is more of a perspective shift — physical, emotional, and conceptual — with limited visuals but a much stronger pull toward oneness and ego death. Most Psychonauts report it as more intense.

No. While 5-MeO-DMT is best known from Bufo alvarius secretions, harvesting has endangered the species, so ours is 100% synthesized. Same molecule, no toads harmed.

Same formulation and potency in both. The peach version adds a flavouring agent to reduce harshness on the throat; raw is unflavoured.

At roughly 7.5–10mg per breakthrough dose, the 200mg/0.5mL cartridge holds about 20–25 and the 400mg/1mL about 40–50. The carrier is 100% propylene glycol with no vitamin E acetate, on a 100% ceramic coil.

Yes — a 510-compatible battery is required for all vape cartridges. We offer batteries on the checkout page if you don't already have one.